MMSE change | ||||||||
---|---|---|---|---|---|---|---|---|
CT + H | CT | Expected | ||||||
Follow-up | N | mean ± SD | 95% CI | N | mean ± SD | 95% CI | P value | |
3 m | 121 | 0.93 ± 2.80 | 0.43 to 1.43 | 70 | −0.05 ± 3.60 | −0.91 to 0.8 | 0.009 | −0.57 |
6 m | 71 | 0.75 ± 2.90 | 0.06 to 1.43 | 33 | 0.27 ± 3.01 | −0.79 to 1.34 | 0.034 | −1.12 |
9 m | 49 | 0.59 ± 3.01 | −0.27 to 1.45 | 12 | −0.41 ± 3.92 | −2.9 to 2.07 | 0.077 | −1.64 |
12 m | 52 | −0.05 ± 2.85 | −0.85 to 0.73 | 28 | −1.03 ± 3.12 | −2.24 to 0.17 | 0.009 | −2.17 |
15 m | 53 | −0.32 ± 2.41 | −0.98 to 0.34 | 21 | −1.95 ± 2.65 | −3.16 to −0.74 | 0.008 | −2.89 |
18 m | 26 | −1.42 ± 1.79 | −2.14 to −0.69 | 27 | −3.18 ± 2.21 | −4.04 to −2.32 | 0.010 | −3.43 |
21 m | 23 | −1.08 ± 2.36 | −1.83 to −0.33 | 11 | −3.36 ± 2.54 | −5.07 to −1.65 | 0.014 | −3.65 |
24 m | 30 | −1.40 ± 2.37 | −2.28 to −0.51 | 26 | −3.92 ± 2.26 | −4.83 to −3.01 | 0.000 | −4.52 |