Fig. 5
Coptis Chinensis inhibited Glioma tumor growth. U87 cells (3 × 106) were subcutaneously injected into the right axilla of Balb/c nude mice. Two days after injecting, Coptis Chinensis (20 and 10 mg/per mouse/day, respectively and distilled water per mouse was administered intragastrically. a, b Tumor volume and tumor photos at different time and various concentrations points. c, d Survival and weight at different days. Data are presented as mean ± SD from three independent experiments. *, P < 0.05; **, P < 0.01; ***, P < 0.001 compared with the control group