Skip to main content

Table 4 Neuropharmacological effect of Lepisanthes rubiginosa L. on mice in Hole Board method

From: Phytochemical and pharmacological evaluation of ethanolic extract of Lepisanthes rubiginosa L. leaves

Groups

No. of head dipping (mean ± SEM)

O min

30 min

60 min

90 min

120 min

Control (1% tween-80 water)

26.5 ± 1.04

29.3 ± 2.99

30.8 ± 4.30

31.0 ± 1.47

35.3 ± 2.20

Standard (Diazepam 1 mg/kg)

29.5 ± 2.40

17.8 ± 1.50*

15.3 ± 1.00*

13.3 ± 0.85***

11.0 ± 1.08***

Extract 250 mg/kg

28.8 ± 1.44

23.5 ± 0.65

19.5 ± 1.00*

16.5 ± 1.50**

15.0 ± 1.80***

Extract 500 mg/kg

26.3 ± 1.40

22.5 ± 1.44

18.5 ± 1.50*

15.5 ± 0.96***

10.5 ± 1.20***

  1. Here, *p < 0.05, **p < 0.01 and ***p < 0.001 when compared with control group. SEM: standard error of mean, n = 5