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Table 3 Neuropharmacological effect of Lepisanthes rubiginosa L. on mice in Open Field method

From: Phytochemical and pharmacological evaluation of ethanolic extract of Lepisanthes rubiginosa L. leaves

Groups

No. of square crossed (mean ± SEM)

O min

30 min

60 min

90 min

120 min

Control (1% tween-80 water)

38.5 ± 3.0

35.8 ± 1.9

37 ± 3.8

38.1 ± 2.1

42.2 ± 3.03

Standard (Diazepam 1 mg/kg)

36.3 ± 1.9

25.8 ± 1.8**

22.3 ± 1.9*

18.5 ± 1.6***

16.7 ± 2.1***

Extract 250 mg/kg

42.0 ± 6.8

28.3 ± 1.3*

24.8 ± 2.3*

23.3 ± 2.3**

20.8 ± 1.6***

Extract 500 mg/kg

36.0 ± 2.7

26.5 ± 2.5*

23.0 ± 2.3*

21.0 ± 2.6**

19.9 ± 1.7****

  1. Here, *p < 0.05, **p < 0.01 and ***p < 0.001 when compared with control group. SEM: standard error of mean, n = 5