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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Blockade of nicotine sensitization by methanol extracts of Glycyrrhizae radix mediated via antagonism of accumbal oxidative stress

Fig. 4

Effect of MEGR on the Nrf2 and HO-1 expressions in the nicotine-sensitized NaccSh. Immediately after the behavioral test, the protein levels of a cytoplasmic HO-1 and b cytoplasmic and c nuclear Nrf2 in the NaccSh were evaluated by Western blot assays. All data are expressed as means ± SEM (n = 4). Nic: nicotine, S: saline, H3: Histone H3, S: saline, DW: distilled water, MEGR: methanol extract of G. radix, MEGR180: 180 mg/kg/day MEGR. # P < 0.05, ## P < 0.01 versus S/DW/S group; $ P < 0.05, $$ P < 0.01 versus Nic/DW/Nic group (one-way ANOVA followed by Newman-Keuls post-hoc test)

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