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Table 4 Effect of MMMC on the PGE2 content in ethanol-induced gastric tissue of rats

From: Synergistic gastroprotective activity of methanolic extract of a mixture of Melastoma malabathricum and Muntingia calabura leaves in rats

Pre-treatment

Ratio

Dose (mg/kg)

PGE2 (pg/mL)

Normal

 

–

188.10 ± 1.70

2% Tween 80

 

–

159.20 ± 0.93*

Ranitidine

 

100

186.40 ± 4.93***

MMMC

1:1

15

174.30 ± 2.65

150

188.40 ± 4.40***

300

193.40 ± 5.98***

1:3

15

173.40 ± 3.93

150

183.40 ± 3.43***

300

192.40 ± 4.72***

3:1

15

162.30 ± 5.79

150

172.20 ± 2.73

300

185.20 ± 3.34***

  1. Data are presented as mean ± S.E.M. Sixty rats (n = 6 in each group) were used in this study. Statistical analysis was performed using the one-way ANOVA followed by Dunnet’s multiple comparison tests. *P < 0.05,**P < 0.01 and ***P < 0.001 as compared to ulcer control group
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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