Skip to main content

Table 3 Antioxidant activity of MMMC against ethanol-induced gastric ulcer in stomach tissue of rats 

From: Synergistic gastroprotective activity of methanolic extract of a mixture of Melastoma malabathricum and Muntingia calabura leaves in rats

Pre-treatment

Ratio

Dose (mg/kg)

CAT (nmol/min/mL)

SOD (U/mg protein)

GSH (μM/mg protein)

MDA (ng/mL)

Normal

 

–

60.47 ± 2.251

4.72 ± 0.364

43.28 ± 1.118

11.42 ± 0.577

2% Tween 80

 

–

44.11 ± 1.591***

1.56 ± 0.240***

6.606 ± 1.175***

75.00 ± 1.732***

Ranitidine

 

100

66.11 ± 1.569***

3.20 ± 0.381*

23.68 ± 1.037***

15.00 ± 1.693***

MMMC

1:1

15

66.27 ± 1.439***

2.60 ± 0.469*

35.61 ± 1.651***

33.07 ± 2.214***

150

67.01 ± 1.579***

3.94 ± 0.351***

35.80 ± 0.578***

31.44 ± 1.605***

300

69.54 ± 1.846***

3.96 ± 0.365***

38.48 ± 0.955***

26.21 ± 1.707***

1:3

15

68.09 ± 1.932***

2.70 ± 0.327*

39.46 ± 1.878***

46.11 ± 0.824**

150

66.58 ± 2.120***

3.65 ± 0.222***

38.47 ± 0.716***

36.11 ± 1.883***

300

63.51 ± 2.016**

3.46 ± 0.361**

30.49 ± 1.280***

35.83 ± 2.455***

3:1

15

69.03 ± 1.449***

2.66 ± 0.372*

32.27 ± 1.196***

63.06 ± 2.544*

150

68.33 ± 1.456***

3.79 ± 0.329***

42.22 ± 0.705***

41.11 ± 1.321***

300

64.51 ± 1.965**

3.82 ± 0.362***

33.36 ± 1.224***

38.22 ± 1.833***

  1. Data are presented as mean ± S.E.M. Sixty rats (n = 6 in each group) were used in this study. Statistical analysis was performed
  2. using the one-way ANOVA followed by Dunnet’s multiple comparison tests. *P < 0.05,**P < 0.01 and ***P < 0.001 as compared to ulcer control group