Fig. 5

Effect of CLSE on HUVECs capillary tube formation. a. After HUVECs were seeded in matrigel-coated plates and incubated with conditioned media from HCT116 cells treated with DFO (100 μM) and CLSE (0.5, 1 mg/mL) for 24 h. Representative images showing HUVEC tube formation following treatment with conditioned media collected from CLSE-treated HCT116 cells (magnification: ×40). b. Number of branching points per unit area following treatment with conditioned media. ** p < 0.01 versus untreated control group. ^### p < 0.001 versus DFO-only group. Data are mean ± SD (n = 3). CLSE, Coix lacryma-jobi var. ma-yuen Strapt sprout extract; HUVECs, human umbilical vein endothelial cells; SD, standard deviation