Effects of dietary supplementation with a standardized aqueous extract of Terminalia chebula fruit (AyuFlex®) on joint mobility, comfort, and functional capacity in healthy overweight subjects: a randomized placebo-controlled clinical trial

Table 8 VAS scores following leg extension

Visit	AyuFlex1 (n = 56)	AyuFlex2 (n = 66)	Placebo (n = 50)	p value
				Overall^a	AF1 + AF2 vs PBO	AF1 vs PBO	AF2 vs PBO	AF1 vs AF2
Overall^a				0.125	*0.046*	0.258	*0.031*	0.584
0	4.1 (±2.5)	4.2 (±3.3)	3.9 (±2.6)
14	3.6 (±2.3)	4.2 (±3.3)	3.7 (±2.8)		0.966	0.409	0.463	0.088
42	3.0 (±2.3)	3.4 (±3.0)	3.6 (±2.6)		0.122	*0.045*	0.392	0.292
84	2.2 (±2.1)	2.3 (±2.9)	3.1 (±2.5)		*0.010*	*0.010*	*0.033*	0.668
Changes to Measures of VAS Score Following Leg Extension^b
	−1.9 (±2.2)	−1.8 (±2.5)	−0.8 (±2.5)	*0.048*	*0.039*	*0.022*	*0.043*	0.717

^aOverall p value using mean changes over time amoung the listed group/s using a Repeated Measures ANCOVA
^bThis was determined using Post Score Subtracted from Day 0
Values Presented as Mean ± Standard Deviation
Values determined to be significant (p = <0.05) indicated

ISSN: 2662-7671