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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Modulation of hippocampal neuronal activity by So-ochim-tang-gamibang in mice subjected to chronic restraint stress

Fig. 4

Regulation of GAP-43 levels in the hippocampus by SOCG treatment in CRS animals. a Western blot analysis of GAP-43 in the hippocampal tissue. Images in the upper panel show the representatives from 4 independent experiments, and quantitation of protein band intensity relative to actin control are shown in the lower panel. *P < 0.05. (One-way ANOVA, n = 4). b Immunohistochemical analysis of GAP-43 in the CA3 region. GAP-43 signals were seen in the striatum oriens (arrows) and striatum radiatum (arrowheads) besides CA3 pyramidal cell layer. c GAP-43 signals in the dentate gyrus. GAP-43 signals were observed clearly in the inner molecular layer (arrowheads), but rarely seen from the granule cell layer (GCL). Scale bars in (b) and (c): 200 μm

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