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Table 9 Clinical chemistry data for female rats treated with JDHY granules for 13 weeks

From: Subchronic toxicity of herbal compound “Jiedu Huayu” granules in rats

Dose (g/kg/d) 0 80 100 130
Females
 AST(U/L) 208.34 ± 47.04a 212.76 ± 79.64 217.31 ± 70.60 212.25 ± 89.47
 ALT(U/L) 60.57 ± 10.31 60.10 ± 11.25 58.33 ± 11.02 61.53 ± 11.47
 ALP(U/L) 237.88 ± 86.37 238.82 ± 78.02 227.31 ± 66.74 232.38 ± 85.91
 TP(g/L) 84.12 ± 4.34 83.25 ± 8.49 80.47 ± 6.27 81.14 ± 5.41
 ALB(g/L) 41.94 ± 5.24 42.61 ± 4.70 41.98 ± 5.82 41.43 ± 6.42
 TBIL(umol/L) 8.23 ± 2.46 6.80 ± 2.88 8.59 ± 2.99 9.63 ± 3.09
 CHOL(mmol/L) 1.49 ± 0.52 1.61 ± 0.49 1.58 ± 0.52 1.54 ± 0.37
 TG(mmol/L) 0.32 ± 0.07 0.36 ± 0.11 0.37 ± 0.09 0.35 ± 0.07
 GLU(mmol/L) 7.35 ± 0.72 7.20 ± 0.64 7.42 ± 0.61 7.57 ± 0.92
 BUN(mmol/L) 6.51 ± 1.34 6.24 ± 1.36 6.35 ± 1.58 6.44 ± 1.18
 Cr(umol/L) 98.63 ± 11.70 95.38 ± 15.75 96.72 ± 12.43 97.71 ± 12.70
 CK(U/L) 155.77 ± 28.07 150.13 ± 26.80 149.74 ± 26.82 144.18 ± 28.09
 Na+(mmol/L) 145.14 ± 17.59 148.75 ± 13.95 146.38 ± 11.86 144.94 ± 19.28
 K+(mmol/L) 4.81 ± 0.92 5.34 ± 0.90 5.23 ± 1.12 4.93 ± 1.03
 Cl(mmol/L) 108.20 ± 5.95 105.80 ± 8.25 106.10 ± 8.55 107.30 ± 9.20
  1. All samples were collected from five rats in each group
  2. aData are given as mean ± SD
  3. ANOVA analysis indicated no statistical significance P > 0.05