Table 9 Clinical chemistry data for female rats treated with JDHY granules for 13 weeks
From: Subchronic toxicity of herbal compound “Jiedu Huayu” granules in rats
Dose (g/kg/d) | 0 | 80 | 100 | 130 |
|---|---|---|---|---|
Females | ||||
AST(U/L) | 208.34 ± 47.04a | 212.76 ± 79.64 | 217.31 ± 70.60 | 212.25 ± 89.47 |
ALT(U/L) | 60.57 ± 10.31 | 60.10 ± 11.25 | 58.33 ± 11.02 | 61.53 ± 11.47 |
ALP(U/L) | 237.88 ± 86.37 | 238.82 ± 78.02 | 227.31 ± 66.74 | 232.38 ± 85.91 |
TP(g/L) | 84.12 ± 4.34 | 83.25 ± 8.49 | 80.47 ± 6.27 | 81.14 ± 5.41 |
ALB(g/L) | 41.94 ± 5.24 | 42.61 ± 4.70 | 41.98 ± 5.82 | 41.43 ± 6.42 |
TBIL(umol/L) | 8.23 ± 2.46 | 6.80 ± 2.88 | 8.59 ± 2.99 | 9.63 ± 3.09 |
CHOL(mmol/L) | 1.49 ± 0.52 | 1.61 ± 0.49 | 1.58 ± 0.52 | 1.54 ± 0.37 |
TG(mmol/L) | 0.32 ± 0.07 | 0.36 ± 0.11 | 0.37 ± 0.09 | 0.35 ± 0.07 |
GLU(mmol/L) | 7.35 ± 0.72 | 7.20 ± 0.64 | 7.42 ± 0.61 | 7.57 ± 0.92 |
BUN(mmol/L) | 6.51 ± 1.34 | 6.24 ± 1.36 | 6.35 ± 1.58 | 6.44 ± 1.18 |
Cr(umol/L) | 98.63 ± 11.70 | 95.38 ± 15.75 | 96.72 ± 12.43 | 97.71 ± 12.70 |
CK(U/L) | 155.77 ± 28.07 | 150.13 ± 26.80 | 149.74 ± 26.82 | 144.18 ± 28.09 |
Na+(mmol/L) | 145.14 ± 17.59 | 148.75 ± 13.95 | 146.38 ± 11.86 | 144.94 ± 19.28 |
K+(mmol/L) | 4.81 ± 0.92 | 5.34 ± 0.90 | 5.23 ± 1.12 | 4.93 ± 1.03 |
Cl−(mmol/L) | 108.20 ± 5.95 | 105.80 ± 8.25 | 106.10 ± 8.55 | 107.30 ± 9.20 |