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Table 11 Organ coefficient for female rats treated with JDHY granules for 13 weeks

From: Subchronic toxicity of herbal compound “Jiedu Huayu” granules in rats

Dose (g/kg/d)

0

80

100

130

Females

 Heart

0.31 ± 0.03a

0.28 ± 0.03

0.27 ± 0.04

0.33 ± 0.09

 Liver

3.27 ± 0.44

3.27 ± 0.45

3.18 ± 0.67

3.26 ± 0.38

 Spleen

0.30 ± 0.12

0.34 ± 0.11

0.35 ± 0.12

0.35 ± 0.11

 Lung

0.55 ± 0.11

0.61 ± 0.26

0.63 ± 0.28

0.73 ± 0.37

 Kidney

0.61 ± 0.08

0.64 ± 0.08

0.64 ± 0.08

0.60 ± 0.07

 Brain

0.51 ± 0.07

0.47 ± 0.04

0.53 ± 0.09

0.45 ± 0.07

 Thymus

0.17 ± 0.08

0.22 ± 0.06

0.22 ± 0.08

0.18 ± 0.11

 Renicapsule

0.02 ± 0.006

0.02 ± 0.004

0.02 ± 0.005

0.02 ± 0.006

 Uterus

0.23 ± 0.06

0.24 ± 0.03

0.25 ± 0.12

0.21 ± 0.05

 Oarium

0.06 ± 0.01

0.07 ± 0.02

0.05 ± 0.01

0.06 ± 0.02

  1. All samples were collected from five rats in each group
  2. aData are given as mean ± SD
  3. ANOVA analysis indicated no statistical significance P > 0.05