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Table 4 Effects of various fractions of R. hastatus leaves on phase II antioxidant enzymes and DNA fragmentation

From: Evaluation of Rumex hastatus leaves against hepatic fibrosis: a rat model

Group

GST (nM/min/mg protein)

GPx (nM/min/mg protein)

GR (nM/min/mg protein)

GSH (μM/g tissue)

QR (nM/min/mg protein)

DNA damages %

Control

240.51 ± 6.19++

180.42 ± 3.25++

200.29 ± 3.13++

32.86 ± 3.22++

148.55 ± 2.22++

8.13 ± 1.03++

Oil + DMSO

248.35 ± 3.75++

179.31 ± 3.56++

202.42 ± 3.16++

33.41 ± 4.05++

149.63 ± 1.79++

8.28 ± 2.08++

CCl4

125.85 ± 5.79**

83.48 ± 2.39**

103.38 ± 2.87**

12.36 ± 2.68**

78.65 ± 1.37**

43.68 ± 1.37**

Sily + CCl4

196.00 ± 5.38++

148.84 ± 2.77++

176.32 ± 2.17++

24.75 ± 3.72++

120.17 ± 1.57++

14.02 ± 1.80++

ELR + CCl4

180.58 ± 5.39++

132.23 ± 2.38++

170.73 ± 2.26++

25.27 ± 2.38++

115.17 ± 1.21++

16.31 ± 2.02++

MLR + CCl4

187.48 ± 4.03++

120.78 ± 3.02++

154.92 ± 3.96++

21.58 ± 1.98++

108.75 ± 2.08++

14.19 ± 1.46++

ELR alone

249.98 ± 3.34++

185.23 ± 2.24++

201.29 ± 4.74++

35.29 ± 2.24++

149.12 ± 1.56++

6.89 ± 1.31++

MLR alone

247.34 ± 3.27++

184.34 ± 2.87++

204.38 ± 3.28++

34.26 ± 2.75++

150.12 ± 1.10++

7.00 ± 1.31++

  1. Values are Mean ± SD (06 number). Sily = Silymarin
  2. **indicate significance from the control group at P < 0.05 and P < 0.01 probability level
  3. ++indicate significance from the CCl4 group at P < 0.05 and P < 0.01 probability level