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Table 1 Mean number of revertant colonies per plate (±SD) in Salmonella typhimurium TA98, TA100 and TA102 exposed to different concentrations of the compounds isolated from C. microphyllum to measure mutagenicity

From: Isolation and characterization of the compounds responsible for the antimutagenic activity of Combretum microphyllum (Combretaceae) leaf extracts

Concentration μg/ml 500 50 5
S. typhimurium TA98
 n-Tetracosanol 30.00 ± 7.81 35.67 ± 9.71 23.67 ± 4.51
 Eicosanoic acid 27.77 ± 1.53 29.33 ± 4.04 28.67 ± 5.51
 Arjunolic acid 33.00 ± 2.65 28.33 ± 3.78 26.67 ± 1.15
Negative/solvent blank 28.60 ± 5.32 Positive 2 μg/ml 4-NQO 239.33 ± 33.20
S. typhimurium TA100
 n-Tetracosanol 125.00 ± 8.18 121.33 ± 2.52 127.00 ± 7.21
 Eicosanoic acid 108.67 ± 5.03 102.67 ± 4.73 112.33 ± 2.89
 Arjunolic acid 109.00 ± 8.72 104.33 ± 2.52 107.33 ± 1.15
Negative/solvent blank 107.00 ± 4.85 Positive 1 μg/ml 4-NQO 864.00 ± 9.77
S. typhimurium TA102
 n-Tetracosanol 294.33 ± 20.74 271.00 ± 4.58 286.67 ± 8.50
 Eicosanoic acid 292.33 ± 5.51 278.33 ± 7.57 288.00 ± 10.82
 Arjunolic acid 287.00 ± 15.39 280.67 ± 10.69 288.67 ± 28.68
Negative/solvent blank 282.40 ± 15.53 Positive 1 μg/ml MMC 1241.67 ± 7.77