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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Preventive effects of the novel antimicrobial peptide Nal-P-113 in a rat Periodontitis model by limiting the growth of Porphyromonas gingivalis and modulating IL-1β and TNF-α production

Fig. 4

a Linear correlation curve of the P. gingivalis’ DNA copy number and cytokines in periodontal tissue (IL-1β and TNF-α). The integrated optical densities of IL-1β and TNF-α were calculated on the basis of immunohistochemical staining. The levels of IL-1β and TNF-α in rat periodontal tissue showed a significant positive linear correlation with DNA copy number of P. gingivalis (P < 0.05). b Linear correlation curve of the total bacteria DNA copy number and cytokines in periodontal tissue (IL-1β and TNF-α). The integrated optical densities of IL-1β and TNF-α were calculated on the basis of immunohistochemical staining. There was not a significant positive linear correlation between IL-1β or TNF-α expression levels in rat periodontal tissue and DNA copy number of total bacteria (P > 0.05)

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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