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Table 5 In situ evaluation of the effect of SCG and MCG on liver treated with SCG and MCG post CCl4 -induced hepatotoxicity

From: Hepatoprotective and antioxidant effects of single clove garlic against CCl4-induced hepatic damage in rabbits

 

C

T

TS

TM

Cellular inflammation

ــ

+++

++

++

 

0.0

4.25 ± 2.63a**

2.25 ± 0.96

2.50 ± 1.29

Necrosis

ــ

++++

++

++

 

0.0

5.25 ± 2.06***

2.25 ± 0.50b*

2.75 ± 0.96b*

Congestion

+

++++

++

++

 

1.25 ± 0.50

36.12 ± 15.45a***

20.50 ± 5.75

18.25 ± 2.5

Ballooned hepatocytes

+

++++

+++

+++

 

3.25 ± 1.89

39.50 ± 5.45a****

22.50 ± 8.96b**

26.0 ± 5.1 b*

Vasodilation

+

++++

++

++

 

1.75 ± 0.50

6.0 ± 2.16a**

2.50 ± 1.29b*

2.75 ± 1.71b*

Steatosis

ــ

++++

++

++

 

0.0

22 ± 8.49a***

6.5 ± 3.11b**

8.5 ± 4.51b*

  1. Results presented are means ± SD; (n = 6)
  2. C Normal control, T CCl4, TS CCl4 + SCG, TM CCl4 + MCG
  3. Damages graded as follows: -, absent; +, trace (1–25%); ++, mild (25–50%); +++, moderate (50–75%); ++++, severe (75–100%)
  4. * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001
  5. avs C group; bvs T group