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Table 2 The detailed information of the cell experiments

From: The cardioprotective and antiarrhythmic effects of Nardostachys chinensis in animal and cell experiments

Study

Cell

Intervention

Groups

Target

Outcome measure

Xiangyu Li et al. 2013

The normal isolated ventricular myocytes of rats

The volatile oil of NC

The volatile oil of NC group-1 (1 μg/g)

The volatile oil of NC group-2 (3 μg/g)

The volatile oil of NC group-3 (5 μg/g)

The volatile oil of NC group-4 (10 μg/g)

The volatile oil of NC group-5 (20 μg/g)

The volatile oil of NC group-6 (50 μg/g)

Ik; Ik1

Dose-response; I-V curve; Activation curve; Inactivation curve

Qizhu Tang et al. 2004

The normal isolated ventricular myocytes of rabbits

The extract of NC

The control group

The extract of NC group-1 (5 g/L)

The extract of NC group-2 (10 g/L)

INa; ICa-L

Dose-response; I-V curves

Ming Cao et al. 2010

The normal isolated ventricular myocytes of rats

The volatile oil of NC

The volatile oil of NC group-1 (3 μg/g)

The volatile oil of NC group-2 (5 μg/g)

The volatile oil of NC group-3 (10 μg/g)

The volatile oil of NC group-4 (20 μg/g)

The volatile oil of NC group-5 (50 μg/g)

ICa-L

Dose-response; I-V curve; Activation curve; Inactivation curve

Yuanwei Liu et al. 2009

The normal isolated ventricular myocytes of rats

The extract of NC

The control group

The extract of NC group-2 (10 g/L)

INa; Ito

I-V curve

Tao Yang et al. 2009

The normal isolated ventricular myocytes of rats

The volatile oil of NC

The volatile oil of NC group-1 (1 μg/g)

The volatile oil of NC group-2 (3 μg/g)

The volatile oil of NC group-3 (5 μg/g)

The volatile oil of NC group-4 (10 μg/g)

The volatile oil of NC group-5 (100 μg/g)

INa

Dose-response; I-V curve; Activation curve; Inactivation curve

Langjie Hu et al. 2009

The normal isolated ventricular myocytes of rats

The volatile oil of NC

The volatile oil of NC group-1 (3 μg/g)

The volatile oil of NC group-2 (6 μg/g)

The volatile oil of NC group-3 (10 μg/g)

The volatile oil of NC group-4 (20 μg/g)

Ito

Dose-response; I-V curve; Activation curve; Inactivation curve

Yuzhi Ge et al. 2009

Nav 1.5-HEK cell

The volatile oil of NC

The volatile oil of NC group-1 (3 ppm)

The volatile oil of NC group-2 (10 ppm)

INa

Dose-response; Voltage-dependent curve

Zhiting Wu et al. 2009

Nav 1.5-HEK cell

The volatile oil of NC

The volatile oil of NC group (10 ppm)

INa

I-V curve; G-V curve

Yanyang Liu et al. 2013

Nav 1.5-HEK cell

The volatile oil of NC

The volatile oil of NC group (5 ppm)

INa

Frequency-dependent curve

  1. I-V Current-voltage relationship, G-V Conductance-voltage relationship