Study | Cell | Intervention | Groups | Target | Outcome measure |
---|---|---|---|---|---|
Xiangyu Li et al. 2013 | The normal isolated ventricular myocytes of rats | The volatile oil of NC | The volatile oil of NC group-1 (1 μg/g) The volatile oil of NC group-2 (3 μg/g) The volatile oil of NC group-3 (5 μg/g) The volatile oil of NC group-4 (10 μg/g) The volatile oil of NC group-5 (20 μg/g) The volatile oil of NC group-6 (50 μg/g) | Ik; Ik1 | Dose-response; I-V curve; Activation curve; Inactivation curve |
Qizhu Tang et al. 2004 | The normal isolated ventricular myocytes of rabbits | The extract of NC | The control group The extract of NC group-1 (5Â g/L) The extract of NC group-2 (10Â g/L) | INa; ICa-L | Dose-response; I-V curves |
Ming Cao et al. 2010 | The normal isolated ventricular myocytes of rats | The volatile oil of NC | The volatile oil of NC group-1 (3 μg/g) The volatile oil of NC group-2 (5 μg/g) The volatile oil of NC group-3 (10 μg/g) The volatile oil of NC group-4 (20 μg/g) The volatile oil of NC group-5 (50 μg/g) | ICa-L | Dose-response; I-V curve; Activation curve; Inactivation curve |
Yuanwei Liu et al. 2009 | The normal isolated ventricular myocytes of rats | The extract of NC | The control group The extract of NC group-2 (10Â g/L) | INa; Ito | I-V curve |
Tao Yang et al. 2009 | The normal isolated ventricular myocytes of rats | The volatile oil of NC | The volatile oil of NC group-1 (1 μg/g) The volatile oil of NC group-2 (3 μg/g) The volatile oil of NC group-3 (5 μg/g) The volatile oil of NC group-4 (10 μg/g) The volatile oil of NC group-5 (100 μg/g) | INa | Dose-response; I-V curve; Activation curve; Inactivation curve |
Langjie Hu et al. 2009 | The normal isolated ventricular myocytes of rats | The volatile oil of NC | The volatile oil of NC group-1 (3 μg/g) The volatile oil of NC group-2 (6 μg/g) The volatile oil of NC group-3 (10 μg/g) The volatile oil of NC group-4 (20 μg/g) | Ito | Dose-response; I-V curve; Activation curve; Inactivation curve |
Yuzhi Ge et al. 2009 | Nav 1.5-HEK cell | The volatile oil of NC | The volatile oil of NC group-1 (3Â ppm) The volatile oil of NC group-2 (10Â ppm) | INa | Dose-response; Voltage-dependent curve |
Zhiting Wu et al. 2009 | Nav 1.5-HEK cell | The volatile oil of NC | The volatile oil of NC group (10Â ppm) | INa | I-V curve; G-V curve |
Yanyang Liu et al. 2013 | Nav 1.5-HEK cell | The volatile oil of NC | The volatile oil of NC group (5Â ppm) | INa | Frequency-dependent curve |