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Fig. 6 | BMC Complementary and Alternative Medicine

Fig. 6

From: Effects of Chinese medicinal herbs on expression of brain-derived Neurotrophic factor (BDNF) and its interaction with human breast cancer MDA-MB-231 cells and endothelial HUVECs

Fig. 6

The role of BDNF-TrkB signaling in the L. chuanxiong induced responses within MDA-MB-231 cells. L. chuanxiong-treated MDA-MB-231 cells, without/with anti-BDNF antibody and with/without TrkB inhibitor pretreatment independently were evaluated by MTT assay (a) and migration assay (b, c, d). Furthermore, cells were lysed to allow the proteins present to be analyzed by Western blotting (e). The results were quantified (f) and are expressed as mean + SEM. *, p < 0.05 compared to vehicle group by repeatedly measured one way ANOVA; #, p < 0.05 by Mann Whitney test, $, < 0.05 by the Student’s t test (n = three to five independent experiments in each group)

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