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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: [6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-stimulated insulin secretion pathway in pancreatic β-cells and increases RAB8/RAB10-regulated membrane presentation of GLUT4 transporters in skeletal muscle to improve hyperglycemia in Leprdb/db type 2 diabetic mice

Fig. 5

[6]-Gingerol upregulates Rab27a and Slp4-a in pancreatic islets. Rab27a (a) expression and b protein level, and Slp4-a (c) expression and d protein level in islets isolated from [6]-Gingerol treated (4 weeks, 200 mg/kg/day orally) Leprdb/db mice following an oral glucose load. Values are presented as Mean±SD (n = 8 mice for each group). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, n.s. not significant (Student’s t-test)

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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