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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: Estrogen-like and tissue-selective effects of 7-methoxycoumarin from Ficus umbellata (Moraceae): an in vitro and in vivo study

Fig. 5

Analysis of the rat vaginas. Microphotographs of H&E-stained sections (400×) of vagina (a) and graphic representation of the vaginal epithelial height (b). OVX = Ovariectomized rat treated with vehicle; E2B = Ovariectomized rat treated with estradiol benzoate at the dose of 2 μg/kg. E2B + ICI = Ovariectomized rat co-administered with estradiol benzoate (1.75 μg/kg) and ICI, 182.780 (300 μg/kg). GEN = Ovariectomized rat treated with genistein at the dose of 10 mg/kg BW. MC = Ovariectomized rat treated with 7-methoxycoumarin at the doses of 0.1, 1 and 10 mg/kg BW. MC + E2B = Ovariectomized rat co-administered with estradiol benzoate (1.75 μg/kg) and 7-methoxycoumarin at the doses of 0.1, 1 and 10 mg/kg BW. ** p < 0.01; *** p < 0.001 as compared to OVX group. ### p < 0.001 as compared with E2B group. Lu = lumen of uterus; En = endometrium; St = Stroma

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