Fig. 2

In vitro myelo-protective effect of Phragmitis rhizoma extract and its major component, p-hydroxycinnamic acid. CFU assay using mouse BMNCs was performed in the presence of combination of docetaxel (DTX) and increasing concentrations of a Phragmitis rhizoma extract (EPR, 25–100 μg/ml) or b p-hydroxycinnamic acid (p-HCA, 1–100 μM). The number of colonies per 10⁴ BMNCs that were inoculated on the semi-solid medium was manually counted. Data are represented as means ± SEM of 4 (EPR) or 3 (p-HCA) repeated experiments. ***, p < 0.001 vs. vehicle-treated control (Ctrl); ^#,^## and ^###, p < 0.05, p < 0.01 and p < 0.001 vs. docetaxel only treated group, respectively