Table 4 Effect of different test doses of product on bilirubin, ALT and AST in male and female rats
From: Acute and sub-acute toxicity study of a Pakistani polyherbal formulation
Parameters | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|
Control | 50 mg/kg/day | 100 mg/kg/day | 200 mg/kg/day | Control | 50 mg/kg/day | 100 mg/kg/day | 200 mg/kg/day | |
Bilirubin (mg/dl) | 1.575 ± 0.051 | 0.592** ± 0.011 | 0.602** ± 0.010 | 0.696** ± 0.013 | 1.0 ± 0.063 | 0.64** ± 0.045 | 0.76 ± 0.045 | 1.56** ± 0.060 |
ALT (μ/ml) | 38.42 ± 0.229 | 8.4** ± 0.172 | 8.86** ± 0.141 | 6.942** ± 0.102 | 38.47 ± 0.309 | 9.54** ± 0.454 | 9.41** ± 0.383 | 9.28** ± 0.311 |
AST (μ/ml) | 39.9 ± 0.251 | 10.0** ± 0.254 | 8.68** ± 0.154 | 8.62** ± 0.261 | 37.92 ± 0.419 | 10.98** ± 0.503 | 9.54** ± 0.310 | 8.98** ± 0.661 |