In vivo evaluation of hot water extract of Acorus gramineus root against benign prostatic hyperplasia

Table 1 Initial and final body weight, change of body weight and feeding efficiency

Group	No. of Rats	Initial BW (g)	Final BW (g)	BW Gain (g)	FER (%)	Survival Rate (%)
Control	7	404.6 ± 2.4^a	534.4 ± 12.3^b	111.8 ± 10.2^b	1.00 ± 0.09^b	100
BPH	7	406.5 ± 9.2^a	470.6 ± 18.4^a	64.1 ± 11.6^a	0.41 ± 0.07^a	100
BPH + AG 100 mg	7	405.0 ± 8.2^a	451.6 ± 11.3^a	46.6 ± 7.2^a	0.30 ± 0.04^a	100
BPH + AG 250 mg	7	406.2 ± 8.8^a	459.0 ± 11.0^a	52.9 ± 4.5^a	0.35 ± 0.03^a	100
BPH + AG 500 mg	7	403.5 ± 4.3^a	444.9 ± 5.1^a	41.4 ± 5.3^a	0.26 ± 0.03^a	100
Finasteride	7	405.1 ± 9.3^a	455.5 ± 17.4^a	50.5 ± 12.5^a	0.33 ± 0.05^a	100

Data express the mean ± S.E. The letters in the columns indicate statistical differences by Duncan’s multiple range test (p < 0.05). Control: Normal rat supplied with tap water, BPH: Castrated rat supplied with tap water, AG 100: Castrated rat supplied with AG 100 mg/kg of BW daily, AG 250: Castrated rat supplied with AG 250 mg/kg of BW daily, AG 500: Castrated rat supplied with AG 500 mg/kg of BW daily. Data are represented as mean±SEM. a, P<0.05 vs. control, b, P<0.01 vs. control, c, P<0.001 vs. control

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