Fig. 4

Effects of AG on expression of 5-α reductase II, COX-2 and NF-κB p65 phosphorylated protein in the prostate. a Expression of SRD5A2 (steroid 5-α reductase II) (b) The relative density of SRD5A2 was analyzed by densitometry. c Expression of COX-2, phosphorylated NF-κB p65. d The relative density of COX-2 and phosphorylated NF-κB p65. Control: water, BPH: 3 mg.kg testosterone propionate, AG 100, AG 250, AG 500: 3 mg/kg testosterone propionate + AG 100 mg/kg, AG 250 mg/kg, AG 500 mg/kg, respectively, Finasteride: 3 mg/kg testosterone propionate + finasteride 10 mg/kg. Data represented as mean ± SD (n = 7). Significant difference at p < 0.05 compared with the Control group and BPH induced group, respectively