Table 1 Effect of B.orthobotrys on turpentine oil induced joint edema in rats (n = 5, Mean ± SEM)

Arthritic control

(3 ml/kg)

9.44 ± 0.028

10.59 ± 0.022

12.34 ± 0.023

14.98 ± 0.027

16.38 ± 0.028

20.96 ± 0.028

Standard Aspirin

(100 mg/kg)

7.02 ± 0.026***

(25.63)

6.83 ± 0.026***

(35.50)

6.58 ± 0.035***

(46.67)

6.37 ± 0.024***

(57.34)

6.25 ± 0.028***

(61.84)

6.02 ± 0.027***

(71.27)

Aqueous-methanolic extract (50 mg/kg)

7.40 ± 0.021***

(21.61)

7.15 ± 0.021***

(32.48)

6.95 ± 0.030***

(43.67)

6.87 ± 0.026***

(54.13)

6.71 ± 0.026***

(59.03)

6.63 ± 0.024***

(68.36)

Aqueous-methanolic extract (100 mg/kg)

7.19 ± 0.021***

(23.83)

6.87 ± 0.027***

(35.12)

6.61 ± 0.022***

(46.43)

6.54 ± 0.021***

(56.34)

6.33 ± 0.026***

(61.35)

6.10 ± 0.024***

(70.89)

Aqueous-methanolic extract (150 mg/kg)

6.84 ± 0.026***

(27.54)

6.58 ± 0.025***

(37.86)

6.31 ± 0.024***

(48.86)

6.14 ± 0.022***

(59.01)

5.82 ± 0.023***

(64.46)

5.50 ± 0.025***

(73.75)

n-butanol fraction (50 mg/kg)

7.75 ± 0.018***

(17.90)

7.68 ± 0.019***

(27.47)

8.33 ± 0.024***

(32.49)

8.29 ± 0.029***

(44.65)

8.24 ± 0.029***

(49.69)

8.19 ± 0.027***

(60.92)

n-butanol fraction (100 mg/kg)

7.51 ± 0.023***

(20.44)

7.48 ± 0.023***

(29.36)

7.84 ± 0.021***

(36.46)

7.76 ± 0.027***

(48.19)

7.70 ± 0.025***

(52.99)

7.65 ± 0.019***

(63.50)

n-butanol fraction

(150 mg/kg)

7.32 ± 0.021***

(22.45)

7.20 ± 0.021***

(32.01)

7.39 ± 0.021***

(40.11)

7.21 ± 0.021***

(51.86)

7.04 ± 0.028***

(57.02)

6.90 ± 0.023***

(67.08)

Ethyl acetate fraction

(50 mg/kg)

7.96 ± 0.029***

(15.67)

7.86 ± 0.028***

(25.77)

8.44 ± 0.028***

(31.60)

8.41 ± 0.031***

(43.85)

8.05 ± 0.020***

(50.85)

9.10 ± 0.023***

(56.58)

Ethyl acetate fraction

(100 mg/kg)

7.74 ± 0.021***

(18.00)

7.71 ± 0.026***

(27.19)

7.96 ± 0.027***

(35.49)

7.80 ± 0.028***

(47.93)

7.75 ± 0.025***

(52.68)

8.40 ± 0.021***

(59.92)

Ethyl acetate fraction

(150 mg/kg)

7.43 ± 0.027***

(21.29)

7.40 ± 0.026***

(30.12)

7.73 ± 0.021***

(37.35)

7.48 ± 0.017***

(50.06)

7.22 ± 0.025***

(55.92)

7.70 ± 0.030***

(63.26)

Aqueous fraction

(50 mg/kg)

8.24 ± 0.023***

(12.71)

8.11 ± 0.026***

(23.41)

8.60 ± 0.026***

(30.30)

8.92 ± 0.030***

(40.25)

9.13 ± 0.027***

(44.26)

9.58 ± 0.025***

(54.29)

Aqueous fraction

(100 mg/kg)

7.98 ± 0.024***

(15.46)

7.77 ± 0.026***

(26.62)

8.10 ± 0.026***

(34.35)

8.45 ± 0.027***

(43.59)

7.78 ± 0.023***

(52.50)

8.99 ± 0.025***

(57.10)

Aqueous fraction

(150 mg/kg)

7.62 ± 0.021***

(19.27)

7.54 ± 0.021***

(28.80)

7.69 ± 0.028***

(37.68)

7.95 ± 0.023***

(46.92)

7.23 ± 0.033***

(55.86)

8.30 ± 0.027***

(60.40)