Table 4 Fasting plasma glucose and serum lipid levels by group and visit
YY-312 group | Placebo group | P-value* | |||
|---|---|---|---|---|---|
n | Mean ± SD | n | Mean ± SD | ||
FPG (mg/dL) | |||||
Baseline | 30 | 91.5 ± 10.3 | 30 | 91.1 ± 7.7 | 0.843 |
6 weeks | 24 | 93.5 ± 13.3 | 26 | 90.2 ± 11.9 | 0.358 |
12 weeks | 20 | 93.8 ± 13.0 | 19 | 94.3 ± 11.8 | 0.908 |
T-Chol (mg/dL) | |||||
Baseline | 30 | 202.4 ± 40.2 | 30 | 206.8 ± 44.4 | 0.689 |
6 weeks | 24 | 204.4 ± 45.9 | 26 | 211.7 ± 46.5 | 0.579 |
12 weeks | 20 | 203.5 ± 47.1 | 19 | 203.5 ± 33.8 | 0.999 |
TG (mg/dL) | |||||
Baseline | 30 | 111.0 ± 58.6 | 30 | 126.4 ± 107.5 | 0.493 |
6 weeks | 24 | 111.3 ± 56.8 | 26 | 132.3 ± 80.6 | 0.295 |
12 weeks | 20 | 107.4 ± 47.2 | 19 | 120.2 ± 67.9 | 0.496 |
HDL-C (mg/dL) | |||||
Baseline | 30 | 53.1 ± 10.1 | 30 | 57.2 ± 10.5 | 0.128 |
6 weeks | 24 | 48.6 ± 8.7 | 26 | 56.0 ± 11.3 | 0.013 |
12 weeks | 20 | 49.6 ± 8.3 | 19 | 55.3 ± 9.7 | 0.052 |
LDL-C (mg/dL) | |||||
Baseline | 30 | 128.4 ± 31.5 | 30 | 126.8 ± 34.1 | 0.848 |
6 weeks | 24 | 125.9 ± 32.2 | 26 | 125.6 ± 34.2 | 0.978 |
12 weeks | 20 | 128.0 ± 33.5 | 19 | 124.0 ± 28.2 | 0.690 |