Fig. 12
From: Beta-mangostin demonstrates apoptogenesis in murine leukaemia (WEHI-3) cells in vitro and in vivo
Histopathology of the spleen tissues. The image shows (a) healthy BALB/c mice with normal white pulp (green arrow), red pulp (blue arrow) cells plainly visible, contrary to those of the leukaemic mice in whom the white pulp has expanded at the expense of the red pulp areas (b, c). The histology of the spleen in (d) and (e) of BM treated groups (30, 60 mg/kg) shows the regression of the white pulp and, at the same time, the red pulp has re-extended; this was also observed in the vinblastine group (f)