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Table 1 Glutathione levels in CLE treated PBMC’s and THP-1 cells

From: Centella asiatica modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)

 

Glutathione (μM)

CLE (mg/ml)

24 h treatment

72 h treatment

 

PBMC

THP-1

PBMC

THP-1

Control

1.238 ± 0.007

1.713 ± 0.002

3.842 ± 0.009

1.449 ± 0.002

0.05

1.429 ± 0.007***

4.125 ± 0.004***

9.138 ± 0.082***

1.576 ± 0.007***

0.2

2.984 ± 0.004***

5.603 ± 0.004***

4.972 ± 0.003***

1.568 ± 0.007***

0.4

0.959 ± 0.002***

1.781 ± 0.002***

5.534 ± 0.011***

1.610 ± 0.009***

0.8

1.073 ± 0.015***

2.495 ± 0.005***

9.749 ± 0.015***

1.634 ± 0.004***

  1. (Values expressed as mean ± SD, *** p < 0.0001, compared to the control)