Fig. 4

S. spinosum root extract is more effective than leaves or fruits extract in the induction of glucose uptake. Differentiated 3 T3-L1 adipocytes were treated with leaves a or fruits b S. spinosum extracts at various concentrations or all at 1 mg/ml, with the use of roots extract and insulin (100 nM) as positive control c for 30 min. The uptake of [3H]2-Deoxy-D-glucose into cells was determined as described in Material and Methods. Data are expressed as percent of basal uptake in control cells. The data represents the Mean ± SEM of measurement made on 3 replicates in each of at least 5 independent experiments. *p < 0.05, **p < 0.005, ***p < 0.0005 compared to untreated cells by Student’s t-test