Skip to main content

Advertisement

Table 4 Effect of the methanol extract of H.micranthus leaves on excision wound model (n = 6)

From: Methanol leaves extract Hibiscus micranthus Linn exhibited antibacterial and wound healing activities

Post wounding days Wound surface area (mean ± SEM) in mm2 and percentage of wound contraction
Ointment base Nitrofurazone ointment (0.2%w/w) Extract ointment (5% w/w each) Extract ointment (10% w/w each)
0 220.60 ± 2.713 (0.0) 213.80 ± 7.971 (0.0) 227.80 ± 5.643 (0.0) 230.80 ± 2.871 (0.0)
2 180.80 ± 4.769 (18.04) 161.20 ± 7.010 (24.60) 166.00 ± 9.508 (27.13) 167.80 ± 12.395 (27.30)
4 145.40 ± 7.096 (34.09) 136.00 ± 6.782 (36.39) 119.20 ± 10.851 (47.67) 117.40 ± 9.765 (49.13)
6 113.80 ± 5.643 (48.41) 80.00 ± 8.390 (62.58) 76.20 ± 8.777* (66.55) 83.40 ± 10.028 (63.86)
8 70.80 ± 11.128 (67.91) 44.40 ± 4.261 (79.23) 36.60 ± 5.600* (83.93) 53.60 ± 7.467 (76.78)
10 34.60 ± 4.707 (84.32) 20.60 ± 2.088 (90.36) 16.80 ± 1.497* (92.63) 29.40 ± 5.400 (87.26)
12 19.80 ± 1.428 (91.02) 14.40 ± 2.400 (93.26) 10.80 ± 1.200* (95.26) 11.60 ± 2.400* (94.97)
14 9.40 ± 1.166 (95.74) 7.20 ± 3.200 (96.63) 2.40 ± 0.400 (98.95) 5.20 ± 1.068 (97.75)
16 6.60 ± 0.872 (97.00) 3.80 ± 2.835 (98.22) 1.60 ± 1.666 (99.30) 2.00 ± 1.095 (99.13)
  1. Values in parenthesis indicate percentage of wound contraction.* significant differences at p < 0.05 (statistical analysis was done by one-way analysis of variance (ANOVA) followed by Tukey’s test for multiple comparisons)