TY - JOUR AU - Lloret, A. AU - Fuchsberger, T. AU - Giraldo, E. AU - Vina, J. PY - 2015 DA - 2015// TI - Molecular mechanisms linking amyloid beta toxicity and tau hyperphosphorylation in Alzheimer's disease JO - Free Radic Biol Med VL - 83 UR - https://doi.org/10.1016/j.freeradbiomed.2015.02.028 DO - 10.1016/j.freeradbiomed.2015.02.028 ID - Lloret2015 ER - TY - JOUR AU - Liu, J. AU - Yang, B. AU - Ke, J. AU - Li, W. AU - Suen, W. C. PY - 2016 DA - 2016// TI - Antibody-based drugs and approaches against amyloid-beta species for Alzheimer's disease immunotherapy JO - Drugs Aging VL - 33 UR - https://doi.org/10.1007/s40266-016-0406-x DO - 10.1007/s40266-016-0406-x ID - Liu2016 ER - TY - JOUR AU - Jiang, T. AU - Sun, Q. AU - Chen, S. PY - 2016 DA - 2016// TI - Oxidative stress: a major pathogenesis and potential therapeutic target of antioxidative agents in Parkinson's disease and Alzheimer's disease JO - Prog Neurobiol VL - 147 UR - https://doi.org/10.1016/j.pneurobio.2016.07.005 DO - 10.1016/j.pneurobio.2016.07.005 ID - Jiang2016 ER - TY - JOUR AU - Kim, M. H. AU - Kim, S. H. AU - Yang, W. M. PY - 2014 DA - 2014// TI - Mechanisms of action of phytochemicals from medicinal herbs in the treatment of Alzheimer's disease JO - Planta Med VL - 80 UR - https://doi.org/10.1055/s-0034-1383038 DO - 10.1055/s-0034-1383038 ID - Kim2014 ER - TY - STD TI - Rasool M, Malik A, Qureshi MS, Manan A, Pushparaj PN, Asif M, et al. Recent Updates in the Treatment of Neurodegenerative Disorders Using Natural Compounds. Evid-Based Compl Alt. 2014;979730 http://dx.doi.org/10.1155/2014/979730 ID - ref5 ER - TY - JOUR AU - Afanas'ev, I. B. AU - Dorozhko, A. I. AU - Brodskii, A. V. AU - Kostyuk, V. A. AU - Potapovitch, A. I. PY - 1989 DA - 1989// TI - Chelating and free radical scavenging mechanisms of inhibiotory action of rutin and quercetin in lipid peroxidation JO - Biochem Pharmacol VL - 38 UR - https://doi.org/10.1016/0006-2952(89)90410-3 DO - 10.1016/0006-2952(89)90410-3 ID - Afanas'ev1989 ER - TY - JOUR AU - Song, J. X. AU - Sze, S. C. AU - Ng, T. B. AU - Lee, C. K. AU - Leung, G. P. AU - Shaw, P. C. AU - Tong, Y. AU - Zhang, Y. B. PY - 2012 DA - 2012// TI - Anti-parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models? JO - J Ethnopharmacol VL - 139 UR - https://doi.org/10.1016/j.jep.2011.12.030 DO - 10.1016/j.jep.2011.12.030 ID - Song2012 ER - TY - JOUR AU - Williams, R. J. AU - Spencer, J. P. PY - 2012 DA - 2012// TI - Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease JO - Free Radic Biol Med VL - 52 UR - https://doi.org/10.1016/j.freeradbiomed.2011.09.010 DO - 10.1016/j.freeradbiomed.2011.09.010 ID - Williams2012 ER - TY - JOUR AU - Youdim, K. A. AU - Qaiser, M. Z. AU - Begley, D. J. AU - Rice-Evans, C. A. AU - Abbott, N. J. PY - 2004 DA - 2004// TI - Flavonoid permeability across an in situ model of the blood-brain barrier JO - Free Radic Biol Med VL - 36 UR - https://doi.org/10.1016/j.freeradbiomed.2003.11.023 DO - 10.1016/j.freeradbiomed.2003.11.023 ID - Youdim2004 ER - TY - JOUR AU - Serafini, M. AU - Peluso, I. AU - Raguzzini, A. PY - 2010 DA - 2010// TI - Session 1: antioxidants and the immune system flavonoids as anti-inflammatory agents JO - P Nutr Soc VL - 69 UR - https://doi.org/10.1017/S002966511000162X DO - 10.1017/S002966511000162X ID - Serafini2010 ER - TY - STD TI - Kumar S, Pandey AK. Chemistry and Biological Activities of Flavonoids: An Overview. Sci World J. 2013; 2013: Article ID 162750.doi: 10.1155/2013/162750. ID - ref11 ER - TY - JOUR AU - Baptista, F. I. AU - Henriques, A. G. AU - Silva, A. M. S. AU - Wiltfang, J. AU - Silva, O. A. B. D. E. PY - 2014 DA - 2014// TI - Flavonoids as therapeutic compounds targeting key proteins involved in Alzheimer's disease JO - ACS Chem Neurosci VL - 5 UR - https://doi.org/10.1021/cn400213r DO - 10.1021/cn400213r ID - Baptista2014 ER - TY - JOUR AU - Orhan, I. E. AU - Daglia, M. AU - Nabavi, S. F. AU - Loizzo, M. R. AU - Sobarzo-Sanchez, E. AU - Nabavi, S. M. PY - 2015 DA - 2015// TI - Flavonoids and dementia: an update JO - Curr Med Chem VL - 22 UR - https://doi.org/10.2174/0929867322666141212122352 DO - 10.2174/0929867322666141212122352 ID - Orhan2015 ER - TY - JOUR AU - Elmann, A. AU - Telerman, A. AU - Mordechay, S. AU - Erlank, H. AU - Rindner, M. AU - Ofir, R. AU - Kashman, Y. PY - 2014 DA - 2014// TI - 3,5,4′-Trihydroxy-6,7,3′-trimethoxyflavone protects astrocytes against oxidative stress via interference with cell signaling and by reducing the levels of intracellular reactive oxygen species JO - Neurochem Int VL - 78 UR - https://doi.org/10.1016/j.neuint.2014.09.003 DO - 10.1016/j.neuint.2014.09.003 ID - Elmann2014 ER - TY - JOUR AU - Kueng, W. AU - Silber, E. AU - Eppenberger, U. PY - 1989 DA - 1989// TI - Quantification of cells cultured on 96-well plates JO - Anal Biochem VL - 182 UR - https://doi.org/10.1016/0003-2697(89)90710-0 DO - 10.1016/0003-2697(89)90710-0 ID - Kueng1989 ER - TY - JOUR AU - Wojtunik-Kulesza, K. A. AU - Oniszczuk, A. AU - Oniszczuk, T. AU - Waksmundzka-Hajnos, M. PY - 2016 DA - 2016// TI - The influence of common free radicals and antioxidants on development of Alzheimer's disease JO - Biomed Pharmacother VL - 78 UR - https://doi.org/10.1016/j.biopha.2015.12.024 DO - 10.1016/j.biopha.2015.12.024 ID - Wojtunik-Kulesza2016 ER - TY - JOUR AU - Kaminska, B. AU - Gozdz, A. AU - Zawadzka, M. AU - Ellert-Miklaszewska, A. AU - Lipko, M. PY - 2009 DA - 2009// TI - MAPK signal transduction underlying brain inflammation and gliosis as therapeutic target JO - Anat Rec VL - 292 UR - https://doi.org/10.1002/ar.21047 DO - 10.1002/ar.21047 ID - Kaminska2009 ER - TY - JOUR AU - Zeitlin, R. AU - Patel, S. AU - Burgess, S. AU - Arendash, G. W. AU - Echeverria, V. PY - 2011 DA - 2011// TI - Caffeine induces beneficial changes in PKA signaling and JNK and ERK activities in the striatum and cortex of Alzheimer's transgenic mice JO - Brain Res VL - 1417 UR - https://doi.org/10.1016/j.brainres.2011.08.036 DO - 10.1016/j.brainres.2011.08.036 ID - Zeitlin2011 ER - TY - JOUR AU - Savage, M. J. AU - Lin, Y. G. AU - Ciallella, J. R. AU - Flood, D. G. AU - Scott, R. W. PY - 2002 DA - 2002// TI - Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition JO - J Neurosci VL - 22 ID - Savage2002 ER - TY - JOUR AU - Echeverria, V. AU - Ducatenzeiler, A. AU - Dowd, E. AU - Janne, J. AU - Grant, S. M. AU - Szyf, M. AU - Wandosell, F. AU - Avila, J. AU - Grimm, H. AU - Dunnett, S. B. PY - 2004 DA - 2004// TI - Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the beta-amyloid peptide intracellularly in hippocampal and cortical neurons JO - Neurosci VL - 129 UR - https://doi.org/10.1016/j.neuroscience.2004.07.036 DO - 10.1016/j.neuroscience.2004.07.036 ID - Echeverria2004 ER - TY - JOUR AU - Braithwaite, S. P. AU - Schmid, R. S. AU - He, D. N. AU - Sung, M. L. A. AU - Cho, S. AU - Resnick, L. AU - Monaghan, M. M. AU - Hirst, W. D. AU - Essrich, C. AU - Reinhart, P. H. PY - 2010 DA - 2010// TI - Inhibition of c-Jun kinase provides neuroprotection in a model of Alzheimer's disease JO - Neurobiol Dis VL - 39 UR - https://doi.org/10.1016/j.nbd.2010.04.015 DO - 10.1016/j.nbd.2010.04.015 ID - Braithwaite2010 ER - TY - STD TI - Tare M, Modi RM, Nainaparampil JJ, Puli OR, Bedi S, Fernandez-Funez P, et al. Activation of JNK Signaling Mediates Amyloid-beta-Dependent Cell Death. Plos One. 2011;6(9) ID - ref22 ER - TY - JOUR AU - Andrade, J. P. AU - Assuncao, M. PY - 2012 DA - 2012// TI - Protective effects of chronic green tea consumption on age-related neurodegeneration JO - Curr Pharm Des VL - 18 UR - https://doi.org/10.2174/138161212798918986 DO - 10.2174/138161212798918986 ID - Andrade2012 ER - TY - JOUR AU - Ghasemi, R. AU - Moosavi, M. AU - Zarifkar, A. AU - Rastegar, K. AU - Maghsoudi, N. PY - 2015 DA - 2015// TI - The interplay of Akt and ERK in a beta toxicity and insulin-mediated protection in primary hippocampal cell culture JO - J Mol Neurosci VL - 57 UR - https://doi.org/10.1007/s12031-015-0622-6 DO - 10.1007/s12031-015-0622-6 ID - Ghasemi2015 ER - TY - JOUR AU - Ayaz, M. AU - Junaid, M. AU - Ahmed, J. AU - Ullah, F. AU - Sadiq, A. AU - Ahmad, S. AU - Imran, M. PY - 2014 DA - 2014// TI - Phenolic contents, antioxidant and anticholinesterase potentials of crude extract, subsequent fractions and crude saponins from Polygonum hydropiper L JO - BMC Complement Altern Med VL - 14 UR - https://doi.org/10.1186/1472-6882-14-145 DO - 10.1186/1472-6882-14-145 ID - Ayaz2014 ER - TY - JOUR AU - Ahmad, S. AU - Ullah, F. AU - Ayaz, M. AU - Sadiq, A. AU - Imran, M. PY - 2015 DA - 2015// TI - Antioxidant and anticholinesterase investigations of Rumex hastatus D JO - Don: potential effectiveness in oxidative stress and neurological disorders Biol Res VL - 48 ID - Ahmad2015 ER - TY - STD TI - Bowirrat A, Yassin M, Abir M, Bisharat B. Armaly Z. Traditional and Modern Medicine Harmonizing the Two Approaches in the Treatment of Neurodegeneration. In: Complementary Therapies for the Contemporary Healthcare. edn. Novi Sad: InTech Prepress. 2012:181–212. ID - ref27 ER - TY - JOUR AU - Annweiler, C. AU - Beauchet, O. PY - 2012 DA - 2012// TI - Possibility of a new anti-alzheimer's disease pharmaceutical composition combining memantine and vitamin D JO - Drugs Aging VL - 29 UR - https://doi.org/10.2165/11597550-000000000-00000 DO - 10.2165/11597550-000000000-00000 ID - Annweiler2012 ER - TY - JOUR AU - Romagnoli, R. AU - Baraldi, P. G. AU - Carrion, M. D. AU - Cara, C. L. AU - Cruz-Lopez, O. AU - Preti, D. AU - Tolomeo, M. AU - Grimaudo, S. AU - Cristina, A. AU - Zonta, N. PY - 2008 DA - 2008// TI - Design, synthesis, and biological evaluation of thiophene analogues of chalcones JO - Bioorg Med Chem Lett VL - 16 UR - https://doi.org/10.1016/j.bmc.2008.04.026 DO - 10.1016/j.bmc.2008.04.026 ID - Romagnoli2008 ER - TY - JOUR AU - Abd El Mohsen, M. M. AU - Kuhnle, G. AU - Rechner, A. R. AU - Schroeter, H. AU - Rose, S. AU - Jenner, P. AU - Rice-Evans, C. A. PY - 2002 DA - 2002// TI - Uptake and metabolism of epicatechin and its access to the brain after oral ingestion JO - Free Radic Biol Med VL - 33 UR - https://doi.org/10.1016/S0891-5849(02)01137-1 DO - 10.1016/S0891-5849(02)01137-1 ID - Abd El Mohsen2002 ER - TY - JOUR AU - Ferruzzi, M. G. AU - Lobo, J. K. AU - Janle, E. M. AU - Cooper, B. AU - Simon, J. E. AU - Wu, Q. L. AU - Welch, C. AU - Ho, L. AU - Weaver, C. AU - Pasinetti, G. M. PY - 2009 DA - 2009// TI - Bioavailability of Gallic acid and Catechins from grape seed polyphenol extract is improved by repeated dosing in rats: implications for treatment in Alzheimer's disease JO - J Alzheimers Dis VL - 18 UR - https://doi.org/10.3233/JAD-2009-1135 DO - 10.3233/JAD-2009-1135 ID - Ferruzzi2009 ER - TY - JOUR AU - Matias, I. AU - Buosi, A. S. AU - Gomes, F. C. A. PY - 2016 DA - 2016// TI - Functions of flavonoids in the central nervous system: astrocytes as targets for natural compounds JO - Neurochem Int VL - 95 UR - https://doi.org/10.1016/j.neuint.2016.01.009 DO - 10.1016/j.neuint.2016.01.009 ID - Matias2016 ER - TY - JOUR AU - Jager, A. K. AU - Saaby, L. PY - 2011 DA - 2011// TI - Flavonoids and the CNS JO - Molecules VL - 16 UR - https://doi.org/10.3390/molecules16021471 DO - 10.3390/molecules16021471 ID - Jager2011 ER - TY - JOUR AU - Kam, T. I. AU - Gwon, Y. AU - Jung, Y. K. PY - 2014 DA - 2014// TI - Amyloid beta receptors responsible for neurotoxicity and cellular defects in Alzheimer's disease JO - Cell Mol Life Sci VL - 71 UR - https://doi.org/10.1007/s00018-014-1706-0 DO - 10.1007/s00018-014-1706-0 ID - Kam2014 ER - TY - JOUR AU - Murakami, A. AU - Ohnishi, K. PY - 2012 DA - 2012// TI - Target molecules of food phytochemicals: food science bound for the next dimension JO - Food Funct VL - 3 UR - https://doi.org/10.1039/c2fo10274a DO - 10.1039/c2fo10274a ID - Murakami2012 ER - TY - JOUR AU - Hou, D. X. AU - Kumamoto, T. PY - 2010 DA - 2010// TI - Flavonoids as protein kinase inhibitors for cancer chemoprevention: direct binding and molecular modeling JO - Antiox Redox Signal VL - 13 UR - https://doi.org/10.1089/ars.2009.2816 DO - 10.1089/ars.2009.2816 ID - Hou2010 ER - TY - JOUR AU - Mandour, M. A. AU - Al-Shami, S. A. AU - Al-Eknah, M. M. AU - Hussein, Y. A. AU - El-Ashmawy, I. M. PY - 2013 DA - 2013// TI - The acute and long-term safety evaluation of aqueous, Methanolic and Ethanolic extracts of Achillea Fragrantissima JO - Afr J Pharm Pharmacol VL - 7 UR - https://doi.org/10.5897/AJPP12.1165 DO - 10.5897/AJPP12.1165 ID - Mandour2013 ER -