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Table 5 In vitro α-amylase inhibition of Cynara scolymus leaves extract and acarbose commercial drug

From: Protective effects of Cynara scolymus leaves extract on metabolic disorders and oxidative stress in alloxan-diabetic rats

Sample

Concentration (μg/mL)

% Inhibition

IC 50 (μg/mL)

Acarbose

50

31.05 ± 0.08

14.83

100

67.40 ± 0.59

200

90.35 ± 0.31

Hexane

50

17.46 ± 0.05

-

100

25.63 ± 0.19

200

30.11 ± 0.28

Ethylacetate

50

29.90 ± 0.86

-

100

33.79 ± 1.20

200

47.50 ± 1.43

Butanol

50

53.09 ± 0.88

82.19

100

60.83 ± 1.02

200

79.08 ± 0.97

Ethanol

50

50.18 ± 0.58

72.22

100

69.23 ± 0.84

200

83.71 ± 0.77

Aqueous

50

46.91 ± 1.27

95.78

100

52.20 ± 0.99

200

66.24 ± 1.13

  1. Values are given as means ± S.D. (n = 3)