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Table 2 Effects of G. pensylvanicum and Allopurinol on Sur and XO active in Liver of PO-Induced Hyperuricemic Mice

From: Caffeoylquinic acid derivatives rich extract from Gnaphalium pensylvanicum willd. Ameliorates hyperuricemia and acute gouty arthritis in animal model

Groups Dose (mg/kg) Sur(μmol/L) Liver XO (U/g protein)
Blank - 5606.7 ± 1564.9 11.14 ± 1.06
Model - 10,675.5 ± 3423.7** 54.28 ± 8.17##
Allopurinol 40 4280.1 ± 2229.5## 5.34 ± 0.65**
G. pensylvanicum extract 100 8388.6 ± 1546.3** 10.85 ± 1.53**
  200 7288.3 ± 4615.0** 8.48 ± 0.85**
  400 6012.9 ± 783.6** 6.09 ± 0.45**
  1. Data represent mean ± SEM for 10 mice; # p < 0.05, ## p < 0.01 compared with Blank group (independent samples t-test); * p < 0.05, ** p < 0.01 compared with Model group