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Table 2 Resveratrol reduced the secretion of cytokines and chemokines in LPS-activated THP-1 cells

From: Resveratrol distinctively modulates the inflammatory profiles of immune and endothelial cells

Treatment PGE2 p IL-1β p IL-6 p TNF-α p CXCL10/IP-10
pg/mL pg/mL ng/mL pg/mL pg/mL p
LPS alone 3010 ± 333   4225 ± 261   566 ± 9   12,050 ± 70   20,350 ± 353  
LPS + RES (25 μM) 515 ± 65 0.001 2095 ± 21 0.034 75 ± 4 0.013 11,750 ± 495 0.590 14,700 ± 707 0.028
  1. PMA-treated THP-1 cells were activated with LPS in the absence or presence of 25 μM RES. The secreted metabolites were measured after 24 h of culture. Mean values ±SD of triplicate cultures are shown. p values were calculated between treatments ‘LPS-alone’ versus ‘LPS + RES’