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Table 2 Resveratrol reduced the secretion of cytokines and chemokines in LPS-activated THP-1 cells

From: Resveratrol distinctively modulates the inflammatory profiles of immune and endothelial cells

Treatment

PGE2

p

IL-1β

p

IL-6

p

TNF-α

p

CXCL10/IP-10

pg/mL

pg/mL

ng/mL

pg/mL

pg/mL

p

LPS alone

3010 ± 333

 

4225 ± 261

 

566 ± 9

 

12,050 ± 70

 

20,350 ± 353

 

LPS + RES (25 μM)

515 ± 65

0.001

2095 ± 21

0.034

75 ± 4

0.013

11,750 ± 495

0.590

14,700 ± 707

0.028

  1. PMA-treated THP-1 cells were activated with LPS in the absence or presence of 25 μM RES. The secreted metabolites were measured after 24 h of culture. Mean values ±SD of triplicate cultures are shown. p values were calculated between treatments ‘LPS-alone’ versus ‘LPS + RES’