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Table 1 Production of PGE2 and nitric oxide in LPS-stimulated RAW264.7 cells

From: Resveratrol distinctively modulates the inflammatory profiles of immune and endothelial cells

Metabolite LPS alone LPS + RES (25 μM) p
PGE2 [pg/mL] 6334 ± 306 2816 ± 134 0.010
Nitric oxide (μM) 20.1 ± 0.8 12.1 ± 0.4 0.005
  1. Cells were incubated with 25 μM RES, stimulated with 1 μg/mL LPS and cultured for 24 h. ‘LPS alone’: indicates the value obtained from LPS-stimulated cells (without RES). Results are shown as mean (± SEM) of triplicate cultures obtained in 5 independent experimental series. p values were calculated between treatments ‘LPS-alone’ versus ‘LPS + RES’. Unstimulated cells produced metabolites at <10% of LPS-stimulated cells