Resveratrol distinctively modulates the inflammatory profiles of immune and endothelial cells

Table 1 Production of PGE₂ and nitric oxide in LPS-stimulated RAW264.7 cells

Metabolite	LPS alone	LPS + RES (25 μM)	p
PGE₂ [pg/mL]	6334 ± 306	2816 ± 134	0.010
Nitric oxide (μM)	20.1 ± 0.8	12.1 ± 0.4	0.005

Cells were incubated with 25 μM RES, stimulated with 1 μg/mL LPS and cultured for 24 h. ‘LPS alone’: indicates the value obtained from LPS-stimulated cells (without RES). Results are shown as mean (± SEM) of triplicate cultures obtained in 5 independent experimental series. p values were calculated between treatments ‘LPS-alone’ versus ‘LPS + RES’. Unstimulated cells produced metabolites at <10% of LPS-stimulated cells

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