Skip to main content

Table 7 Albumin denaturation, membrane protection/stabilization and proteinase inhibition potential of methanol extract of the selected plant species

From: Antimicrobial activity, toxicity and anti-inflammatory potential of methanolic extracts of four ethnomedicinal plant species from Punjab, Pakistan

Test sample

  

Percent inhibition

 
 

Conc. (μg/mL)

Albumin denaturation

Membrane protection

Proteinase inhibition

 

25

29.7 ± 1.4

26.1 ± 0.9

26 ± 0.8

A. indica

50

37.1 ± 1.5

29.4 ± 1.1

28.8 ± 1.1

 

100

46.8 ± 1.2

35.7 ± 1.0

35.1 ± 1.1

 

200

61.4 ± 1.0

44.6 ± 1.2

43.9 ± 1.5

IC50

 

129 ± 4.6

247 ± 5.4

256 ± 5.4

Aspirin

 

84.5 ± 1.1

93.7 ± 1.0

97.1 ± 1.1

 

25

43.1 ± 0.8

31.9 ± 0.9

30 ± 1.0

C. pedicellata

50

59.5 ± 0.9

37 ± 1.2

34.8 ± 1.3

 

100

65.6 ± 1.1

47.6 ± 1.3

42.9 ± 1.3

 

200

73.3 ± 1.3

54.5 ± 1.3

52.1 ± 1.5

IC50

 

28 ± 1.1

151 ± 5.0

175 ± 5.2

Aspirin

 

91.8 ± 1.1

110.9 ± 1.3

117.1 ± 1.3

 

25

17.7 ± 1.5

16.7 ± 1.0

16 ± 1.1

M. indicus

50

25.3 ± 1

23.8 ± 1.2

21.9 ± 1.2

 

100

33.6 ± 1.5

24.9 ± 1.4

23.9 ± 1.5

 

200

48.7 ± 1.5

29.8 ± 1.4

27.6 ± 1.5

IC50

 

203 ± 5.6

510 ± 6.6

577 ± 7.2

Aspirin

 

86.2 ± 0.9

95 ± 1.2

105.2 ± 1.3

 

25

39.1 ± 1

30.1 ± 1.0

28.5 ± 1.1

T. terrestris (fruit)

50

57.6 ± 1.1

45 ± 1.1

43.6 ± 1.2

 

100

63.4 ± 1.3

59.7 ± 1.3

59 ± 1.3

 

200

71.8 ± 1.5

68.8 ± 1.5

67.9 ± 1.5

IC50

 

43 ± 1.3

89 ± 2.4

95 ± 2.7

Aspirin

 

89.2 ± 1.1

95.4 ± 1.2

99.9 ± 1.3

 

25

30.7 ± 1.0

28.3 ± 0. 8

27.8 ± 0.9

T. terrestris (leaf)

50

38.3 ± 1.1

30.1 ± 1.0

29.4 ± 1.0

 

100

48.3 ± 1.1

37.3 ± 1.3

36.4 ± 1.3

 

200

63.6 ± 1.3

51.1 ± 1.5

49 ± 1.6

IC50

 

120 ± 3.9

193 ± 4.8

209 ± 5.6

Aspirin

 

84.2 ± 1.2

96.8 ± 1.3

99.7 ± 1.4

  1. Values are means ± SD (n = 3)