Table 4 Glucose and insulin concentrations obtained after the administration of an oral 3 g glucose load to diabetic rabbits (n = 6) treated with an oral metformin dose of 30 mg/kg
Time (min) | Glucose (mg/dL) | Insulin (mUI/L) | ||||
|---|---|---|---|---|---|---|
Standard chow (group 2) | Supplemented chow (group 5) | p valuesa | Standard chow (group 2) | Supplemented chow (group 5) | p valuesa | |
0 | 326.5 ± 85.76 | 329.2 ± 64.50 | 0.953 | 0.492 ± 0.412 | 1.242 ± 0.789 | 0.066 |
30 | 453.9 ± 90.13 | 458.7 ± 108.2 | 0.935 | 1.681 ± 1.288 | 2.930 ± 1.686 | 0.180 |
60 | 515.0 ± 87.21 | 474.2 ± 96.59 | 0.272 | 1.823 ± 1.385 | 3.883 ± 2.227 | 0.083 |
120 | 501.9 ± 63.41 | 426.4 ± 112.5 | 0.233 | 1.755 ± 1.316 | 4.964 ± 2.601 | 0.022 |
180 | 453.9 ± 88.45 | 395.8 ± 115.5 | 0.511 | 1.249 ± 1.142 | 3.617 ± 1.859 | 0.024 |