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Table 4 Glucose and insulin concentrations obtained after the administration of an oral 3 g glucose load to diabetic rabbits (n = 6) treated with an oral metformin dose of 30 mg/kg

From: Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits

Time (min) Glucose (mg/dL) Insulin (mUI/L)
Standard chow (group 2) Supplemented chow (group 5) p valuesa Standard chow (group 2) Supplemented chow (group 5) p valuesa
0 326.5 ± 85.76 329.2 ± 64.50 0.953 0.492 ± 0.412 1.242 ± 0.789 0.066
30 453.9 ± 90.13 458.7 ± 108.2 0.935 1.681 ± 1.288 2.930 ± 1.686 0.180
60 515.0 ± 87.21 474.2 ± 96.59 0.272 1.823 ± 1.385 3.883 ± 2.227 0.083
120 501.9 ± 63.41 426.4 ± 112.5 0.233 1.755 ± 1.316 4.964 ± 2.601 0.022
180 453.9 ± 88.45 395.8 ± 115.5 0.511 1.249 ± 1.142 3.617 ± 1.859 0.024
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