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Table 2 Effect of single doses (i.p.) of EOM in mice (n=3)

From: Toxicity and antitumor potential of Mesosphaerum sidifolium (Lamiaceae) oil and fenchone, its major component

Groups

Dose (mg/kg)

D/T*

Symptoms

Control

-

0/3

None

EOM

300

0/3

Constipation and decreased urination

EOM

300

0/3

Decreased urination, Vocalization and hyperactivity

EOM

2000

3/3

Tremors, convulsions, ataxia, loss of corneal and auricular reflex, cyanosis, loss of muscle tone and no force to grasp

  1. *D/T = Number of dead mice/number of treated mice