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Table 5 ROC Curve of weight gain, brain weight and age of eye opening between neuro-intoxicated, protected and therapeutically treated rat pups compared to healthy control

From: Postnatal treatment using curcumin supplements to amend the damage in VPA-induced rodent models of autism

Parameters

Groups

Area under the curve

Cutoff value

Sensitivity %

Specificity %

Started weight (g)

VPA

0.600

18.900

100.0%

40.0%

VPA-CUR

1.000

22.250

100.0%

100.0%

CUR

0.670

18.250

100.0%

60.0%

Final weight (g)

VPA

0.700

25.450

60.0%

100.0%

VPA-CUR

0.915

77.550

80.0%

90.0%

CUR

0.585

71.300

100.0%

40.0%

Weight Gained

VPA

0.640

8.700

60.0%

100.0%

VPA-CUR

0.800

60.200

60.0%

100.0%

CUR

0.530

52.700

100.0%

40.0%

Brain weight (g)

VPA

0.640

1.415

80.0%

50.0%

VPA-CUR

0.905

1.477

100.0%

80.0%

CUR

0.590

1.364

90.0%

40.0%

Opening eyes after (Days)

VPA

0.570

16.500

50.0%

100.0%

VPA-CUR

0.510

15.500

60.0%

70.0%

CUR

1.000

14.000

100.0%

100.0%