Table 2 Mean ± S.D. together with the independent t-test for Interleukin-6, Interferon Gamma, cytochrome P450, Serotonin, Glutamine, Glutamate together with Glutamate/Glutamine Ratio in neuro-intoxicated, protected and therapeutically treated rat pups compared to healthy control

10

4.50

22.29

12.59 ± 6.07

100.00

0.019

10

3.61

24.96

15.47 ± 7.56

122.86

0.360

10

4.50

11.61

7.96 ± 2.22

63.25

0.044

10

3.61

16.95

9.87 ± 3.86

78.36

0.246

10

206.47

407.59

331.64 ± 87.78

100.00

0.038

10

152.14

343.25

249.08 ± 58.88

75.10

0.024

10

167.86

366.84

244.41 ± 69.94^c

73.70

0.024

10

117.82

359.21

237.26 ± 95.02^c

71.54

0.033

10

33.02

40.16

36.46 ± 1.79

100.00

0.085

10

33.85

42.01

39.11 ± 2.64

107.27

0.017

10

34.62

43.83

37.50 ± 2.82

102.87

0.335

10

34.14

43.83

38.96 ± 2.92

106.85

0.033

10

113.92

169.46

148.75 ± 15.22

100.00

0.228

10

109.57

174.05

140.14 ± 22.04

94.22

0.323

10

85.18

181.05

135.77 ± 32.81

91.28

0.278

10

122.13

215.83

158.84 ± 30.84

106.78

0.366

10

1640.31

2540.39

2186.87 ± 302.70

100.00

0.001

10

1861.71

2549.07

2082.25 ± 216.82

95.22

0.386

10

1456.53

2052.73

1763.15 ± 165.27^c

80.62

0.002

10

1388.51

2324.78

1798.91 ± 274.83^c

82.26

0.008

10

215.20

286.01

249.53 ± 24.68

100.00

0.002

10

235.78

283.18

258.51 ± 14.04

103.60

0.334

10

178.70

283.58

232.05 ± 34.97

92.99

0.213

10

168.81

272.09

206.71 ± 39.12^c

82.84

0.009

10

0.10

0.16

0.116 ± 0.018

100.00

0.063

10

0.11

0.14

0.125 ± 0.011

108.04

0.169

10

0.10

0.16

0.132 ± 0.017

113.83

0.051

10

0.10

0.14

0.115 ± 0.016

99.65

0.963