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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: Castanea sativa Mill. bark extract exhibits chemopreventive properties triggering extrinsic apoptotic pathway in Jurkat cells

Fig. 5

Fraction of apoptotic cells with active caspase-8 (a) and with altered mitochondrial membrane potential (c) after 72 h treatment with 50 μg·mL−1 CSM bark extract. Panels b and d show representative dot plot of cells with active caspase-8 and altered mitochondrial membrane potential respectively. Active caspase-8 and mitochondrial membrane potential were evaluated by FCM as described in Methods. Each bar represents the mean ± SEM of five independent experiments. Data were analyzed by t-test for paired data. *p < 0.05 vs control

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