BMC Complementary Medicine and Therapies

Table 2 Mean and standard error of the P300 latency and amplitude obtained from all subjects

From: Change in the P300 index – a pilot randomized controlled trial of low-frequency electrical stimulation of acupuncture points in middle-aged men and women

		Total (n = 55)						Group difference (AS-NS)	p-value
		Sham (n = 27)			Real (n = 28)
		Before	After	Difference	Before	After	Difference
Latency of P300 (sec)	Fz	0.31 ± 0.06	0.31 ± 0.07	0.00	0.32 ± 0.07	0.30 ± 0.07	−0.02	−0.02	0.39
	Fcz	0.30 ± 0.07	0.29 ± 0.06	−0.01	0.32 ± 0.07	0.30 ± .007	−0.02	−0.01	0.69
	Cz	0.30 ± 0.06	0.28 ± 0.05	−0.02	0.32 ± 0.07	0.30 ± 0.07	−0.02	0.00	0.35
	Cpz	0.30 ± 0.06	0.27 ± 0.07	−0.03	0.31 ± 0.08	0.31 ± 0.07	0.00	0.03	0.13
	Pz	0.31 ± 0.07	0.28 ± 0.08	−0.03	0.31 ± 0.09	0.30 ± 0.08	−0.01	0.02	0.05
Amplitude of P300 (μV)	Fz	3.49 ± 1.35	3.37 ± 1.91	−0.12	3.76 ± 2.24	4.28 ± 2.53	0.52	0.64	0.16
	Fcz	3.28 ± 1.40	3.46 ± 1.90	0.18	3.59 ± 2.05	4.41 ± 2.56	0.82	0.64	0.17
	Cz	3.09 ± 1.23	3.35 ± 1.98	0.26	3.28 ± 1.87	4.17 ± 2.27	0.89	0.63	0.17
	Cpz	2.92 ± 1.23	2.78 ± 1.79	−0.14	3.11 ± 1.93	3.80 ± 2.03	0.69	0.83	0.04
	Pz	2.70 ± 1.24	2.51 ± 1.53	−0.19	2.81 ± 1.70	3.32 ± 1.81	0.51	0.70	0.06

The differences between the groups were calculated by subtracting the change from before and after the stimulation of the Sham group from that of the Real group, which shows the extent of the changes in the Real group compared with those in the Sham group. Compared to the Sham group, the Real group showed a tendency toward an increase in the P300 amplitude, particularly in channel Cpz (F = 4.41, p = 0.04)
Italicized data: A significant increase in P300 amplitude

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