Fig. 1

Effect of the treatment with CS and Flu (positive control) on immobility time in the FST (a) and on locomotor activity in the open field test (b) in the rat submitted to chronic restraint stress procedure. Each column represents the mean ± SEM (n = 8). Significantly different from Vthe eh-NS groups (**; P < 0.01). Significantly different from the Veh-S groups (+; P < 0.05, ++; P < 0.01, +++; P < 0.001)