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Table 4 Effect of solvents extraction on in vivo anti-inflammatory activity of both date seeds

From: Effect of solvents extraction on phytochemical components and biological activities of Tunisian date seeds (var. Korkobbi and Arechti)

 

Edema (10–2/mL) (mean ± SD)

Edema inhibition (%)

Treatment

Dose (mg/kg)

1 h

3 h

5 h

1 h

3 h

5 h

Control

 

34 ± 1,5

59,5 ± 1,7

68,3 ± 1,09

   

KS

Methanol extract

100

27,03 ± 1,9

29,26 ± 1,1*

35,01 ± 0,89*

20,5

50,82

48,74

200

23,08 ± 2,8*

24,11 ± 0,8*

30,13 ± 1,04*

32,11

59,47

55,88

300

19,1 ± 1,5**

23,34 ± 1,8**

28,04 ± 1,65*

43,82

60,77

58,94

Aquous extract

100

25,5 ± 1,07

27,12 ± 2,02*

33,37 ± 1,98*

25

54,42

51,14

200

20,17 ± 2,3*

22,02 ± 1,98**

27,52 ± 2,67*

40,67

62,99

59,70

300

17 ± 2,7**

19,69 ± 1,08**

24,6 ± 2,13*

50

66,90

63,98

Acetone extract 80%

100

29,24 ± 2,1

35,17 ± 2,09*

38,14 ± 2,87*

14

40,89

44,15

200

26,18 ± 1,03

29,04 ± 1,98*

34,21 ± 1,89*

23

51,19

49,91

300

21,41 ± 1,75*

26,3 ± 1,91*

32,12 ± 2,09*

37,02

55,79

52,97

Acetone extract 100%

100

30,09 ± 0,89

37,15 ± 2,09

41,07 ± 2,01*

11,5

37,56

39,86

200

27,23 ± 2,87

32,21 ± 2,02*

39,51 ± 1,09*

19,91

45,86

42,15

300

23,35 ± 1,98*

27,5 ± 1,89*

34,21 ± 1,19*

31,32

53,78

49,91

AS

Methanol extract

100

27,5 ± 1,76

31,15 ± 1,09*

36,29 ± 1,2*

19,11

47,64

46,86

200

24,41 ± 1,57

27,21 ± 2,08*

32,14 ± 1,14*

28,20

54,26

52,94

300

20,06 ± 1,4*

24,5 ± 2**

30,34 ± 2,03*

41

58,82

55,57

Aquous extract

100

26,18 ± 2,34

28,41 ± 2,02

34,21 ± 3,01*

23

52,25

49,91

200

21,5 ± 2,04*

23,34 ± 1,03*

29,02 ± 1,2*

36,76

60,77

57,51

300

18,05 ± 2,01**

21,7 ± 1,65*

27 ± 2,98*

46,91

63,52

60,46

Acetone extract 80%

100

28,5 ± 1,87

35,17 ± 1,05

38,04 ± 2,07*

16,17

40,89

44,30

200

26,18 ± 1,94

31,97 ± 2,3

35,15 ± 1,84*

23

46,26

48,53

300

23,12 ± 1,87*

28,41 ± 2,03

34,21 ± 1,90*

32

52,25

49,91

Acetone extract 100%

100

30,83 ± 1,02

38,38 ± 1,98

45,24 ± 2,03*

9,32

35,49

33,76

200

29,7 ± 1,09

34,29 ± 1,25

41,17 ± 2,5*

12,64

42,36

39,72

300

25,47 ± 2,01

28,17 ± 1,38

35,05 ± 1,76*

25,08

52,65

48,68

Asl

300

22,29 ± 1,09*

25,33 ± 1,34

31,61 ± 1,87

34,44

57,42

53,71

  1. Values are expressed as mean ± S.E.M. (N = 6); ASL: acetyl salicylate of lysine
  2. KS Korkobbi seed, AS Arechti seed
  3. *p ≤ 0.05 significant from the control. **p ≤ 0.01 significant from the control. ***p ≤ 0.001 significant from the control
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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