Fig. 3
From: Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo
Macroscopic signs of arthritis on day 28. Macroscopic signs of arthritis included swelling, redness and deformity in ankle joints. a Normal; (b) Model; (c) MTX; the TRC combination (d) 25 mg/kg; (e) 50 mg/kg; (f) 75 mg/kg. Compared with Normal (a), obvious arthritis symptoms of erythema and edema were observed in Model (b). Different dose (d, e, and f) could relieve the arthritis symptoms and the high dose could significant attenuated edema as MTX