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Fig. 7 | BMC Complementary and Alternative Medicine

Fig. 7

From: (−)-Epicatechin 3-O-β-d-allopyranoside prevent ovariectomy-induced bone loss in mice by suppressing RANKL-induced NF-κB and NFATc-1 signaling pathways

Fig. 7

Proposed intracellular actions of ECAP to suppress RANKL-induced osteoclastogenesis in RAW264.7 cells. ECAP, (−)-Epicatechin 3-O-β-d-allopyranoside; CAII, carbonic anhydrase II; MMP-9, matrix metalloproteinase-9; CAK, cathepsin K; TRAP, tartrate-resistant acid phosphatase; NFATc1, nuclear factor of activated T cells c1; RANKL, receptor activator of nuclear factor kB (NF-kB) ligand

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