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Table 4 Effect of SS on expression of cytoskeleton organization and intra-cellular transportation related proteins

From: Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study

Protein name

protein ID

High

low

protein description

Gsna

P13020

-2.44

-0.44

Gelsolin

Flna

Q8BTM8

-1.35

-0.21

Filamin-A

Lpin1

Q91ZP3

-1.46

-1.40

Phosphatidate phosphatase LPIN1

Racgap

Q9WVM1

-2.35

-1.71

Rac GTPase-activating protein 1

Chp1

P61022

-2.86

-1.42

Calcineurin B homologous protein 1

Rab10

P61027

-4.01

-1.06

Ras-related protein Rab-10

Rab-7a

P51150

-1.77

-0.54

Ras-related protein Rab-7a

Rab-5c

P35278

-2.59

-0.70

Ras-related protein Rab-5C

Nras

P08556

-2.52

-0.61

GTPase Nras

Vps4b

P46467

-2.25

-0.19

Vacuolar protein sorting-associating protein 4B

Cit

P49025

-1.55

-0.73

Citron Rho-interacting kinase

  1. High/Low: indicate fold changes of certain proteins after high dose or low dose of SS administration
  2. All fold changes are relative to Control group