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Table 3 Effects of SS on expression of protein metabolism related proteins

From: Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study

Protein name protein ID fold change time(h) protein description
Effect of SS on expression of translation related proteins
Sfrs5 O35326 1.24 4 Splicing factor, arginine/serine-rich 5
Sfrs7 Q8BL97 1.49 2 Splicing factor, arginine/serine-rich 7
Ptbp1 P17225 1.59 2 Polypyrimidine tract-binding protein 1
Ruxe P62305 -1.38 24 Small nuclear ribonucleoprotein E
Smd2 P62317 -1.17 2 Small nuclear ribonucleoprotein Sm D2
Npm1 Q61937 -1.09 8 Nucleophosmin
Rps16 P14131 -2.29 8 40S ribosomal protein S16
Rpsa P14206 -1.41 8 40S ribosomal protein SA
Rps14 P62264 -1.08 8 40S ribosomal protein S14
Rps24 P62849 -1.09 8 40S ribosomal protein S24
Rps28 P62858 -1.32 24 40S ribosomal protein S28
Rps19 Q9CZX8 -1.40 24 40S ribosomal protein S19
Effect of SS on expression of post-translation modification related proteins
Pmpcb Q9CXT8 3.51 8 Mitochondrial-processing peptidase subunit beta
Hspa2 P17156 1.50 8 Heat shock-related 70 kDa protein 2
Hsp90ab1 P11499 -1.28 8 Heat shock protein HSP 90-beta
P4hb P09103 -1.33 4 Protein disulfide-isomerase
Pdia3 P27773 -1.27 24 Protein disulfide-isomerase A3
Pdia6 Q922R8 -2.38 8 Protein disulfide-isomerase A6
Canx P35564 -1.38 8 Calnexin
Erp44 Q9D1Q6 -1.91 8 Endoplasmic reticulum resident protein 44
Psmd14 O35593 1.37 8 26S proteasome non-ATPase regulatory subunit 14
Pmsa5 Q9Z2U1 1.53 4 Proteasome subunit alpha type-5
Psmb9 P28076 1.23 24 Proteasome subunit beta type-9
  1. Fold change: peak fold change of certain protein expression
  2. Time(h): time point after SS administration when reach peak fold change
  3. All fold changes are relative to Control group (time point 0 h)