Table 1 Effect of JC-001/CDDP and combined treatment on serum creatinine, urea, ALT, AST and albumin
|  | Naïve | Control | CDDP | JC-001 | JC-001/CDDP |
|---|---|---|---|---|---|
Creatinine (mg/dL) | 1.15 ± 0.39 | 1.27 ± 0.41 | 1.67 ± 1.48 | 1.14 ± 0.49 | 1.44 ± 0.67 |
Urea (mg/dL) | 54.12 ± 9.34 | 54.79 ± 6.25 | 52.16 ± 4.05 | 47.55 ± 9.29 | 50.79 ± 6.92 |
ALT (U/L) | 37.50 ± 10.19 | 75.79 ± 50.91* | 89.58 ± 62.74* | 52.66 ± 29.25 | 79.06 ± 64.80 |
AST (U/L) | 245.6 ± 23.2 | 239.8 ± 23.2 | 238.4 ± 27.9 | 251.3 ± 21.27 | 250.5 ± 34.4 |
Albumin (g/dL) | 0.49 ± 0.07 | 0.46 ± 0.05 | 0.47 ± 0.04 | 0.46 ± 0.05 | 0.47 ± 0.04 |