Skip to main content

Table 5 Immunohistochemical expression of pro- and anti-apoptotic proteins in breast tumors treated and non-treated with Tualang honey

From: The anti-cancer effects of Tualang honey in modulating breast carcinogenesis: an experimental animal study

Groups

 

Tumors

1

-ve control

2

(0.2 g/kg TH)

3

(1.0 g/kg TH)

4

(2.0 g/kg TH)

S.E

Total No of tumors developed.

35

16

20

15

 

No. of Caspase-9 positive tumors (% expression)

16 (45.7%)

13 (81.3%)

14 (70.0%)

11 (73.3%)

1.20

No. of Apaf-1 positive tumors (% expression)

15 (42.9%)

15 (93.8%)

16 (80.0%)

11 (73.3%)

1.28

No. of FASLG positive tumors (% expression)

13 (37.1%)

0

0

0

3.75

No. of FADD positive tumors (% expression)

12 (34.3%)

0

0

0

3.64

No. of Bcl-xL positive tumors (% expression)

28 (80.0%)

9 (56.3%)

10 (50.0%)

10 (66.7%)

5.29

No. of ESR1 positive tumors (% expression)

26 (74.28%)

8 (50%)

11 (55%)

9 (60%)

4.86

  1. Kruskal-Wallis test; statistically significant differences between the groups, p < 0.05. Legend: TH Tualang Honey